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Samantha Bussell

Recent Posts

Sep
23
2016

Tissue Vulnerability and Protein Characterization in Alzheimer’s Disease

By Samantha Bussell
Alzheimer’s disease (AD) – the most common form of dementia – is characterized by the aggregation of amyloid β (Aβ), tau in amyloid plaques, and neurofibrillary tangles that spread progressively across brain tissues. However, the mechanisms that govern selective vulnerability of specified tissues is widely debated.
Sep
08
2016

Tissue Variety in Breast Cancer Research

By Samantha Bussell
Resistance to estrogen-deprivation therapy is common in ER+ breast cancer tissue. To better understand this evolution to resistance, genomic characterization of multiple primary tumors is imperative for comprehensive results and identifying therapeutic targets (http://www.nature.com/ncomms/2016/160809/ncomms12498/full/ncomms12498.html#acknowledgments). For researchers, attaining samples that have been confirmed for diagnosis and receptor expression supports the inherent need for accuracy in tissue characterization.
Aug
31
2016

Mutation Analysis in Cancer Research

By Samantha Bussell
At BioIVT, we understand the importance of mutation analysis in cancer research. Our scientists routinely perform DNA and RNA isolation from both FFPE and Fresh Frozen tissues, as well as biofluids. Additionally, we utilize PCR and FISH for the determining the presence and/or location of particular mutations within tissue specimens. Standard mutation analysis is available for lung, skin, and colon cancers, with custom mutation screens available upon request.

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