---
title: BioIVT Blog | Samantha Bussell (2)
description: Learn valuable insights from the world of biotechnology and pharmaceutical research. (2)
---

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## Samantha Bussell

### Recent Posts

## [![](https://blog.bioivt.com/hs-fs/hubfs/Imported_Blog_Media/92316.jpg?width=875&name=92316.jpg) Sep 23 2016 Tissue Vulnerability and Protein Characterization in Alzheimer’s Disease By Samantha Bussell Alzheimer’s disease (AD) – the most common form of dementia – is characterized by the aggregation of amyloid β (Aβ), tau in amyloid plaques, and neurofibrillary tangles that spread progressively across brain tissues. However, the mechanisms that govern selective vulnerability of specified tissues is widely debated.](https://blog.bioivt.com/tissue-vulnerability-protein-characterization-alzheimers-disease)

## [![](https://blog.bioivt.com/hs-fs/hubfs/Imported_Blog_Media/9816.jpg?width=875&name=9816.jpg) Sep 08 2016 Tissue Variety in Breast Cancer Research By Samantha Bussell Resistance to estrogen-deprivation therapy is common in ER+ breast cancer tissue. To better understand this evolution to resistance, genomic characterization of multiple primary tumors is imperative for comprehensive results and identifying therapeutic targets (http://www.nature.com/ncomms/2016/160809/ncomms12498/full/ncomms12498.html#acknowledgments). For researchers, attaining samples that have been confirmed for diagnosis and receptor expression supports the inherent need for accuracy in tissue characterization.](https://blog.bioivt.com/tissue-variety-breast-cancer-research)

## [![](https://blog.bioivt.com/hs-fs/hubfs/Imported_Blog_Media/83116.jpg?width=875&name=83116.jpg) Aug 31 2016 Mutation Analysis in Cancer Research By Samantha Bussell At BioIVT, we understand the importance of mutation analysis in cancer research. Our scientists routinely perform DNA and RNA isolation from both FFPE and Fresh Frozen tissues, as well as biofluids. Additionally, we utilize PCR and FISH for the determining the presence and/or location of particular mutations within tissue specimens. Standard mutation analysis is available for lung, skin, and colon cancers, with custom mutation screens available upon request.](https://blog.bioivt.com/mutation-analysis-cancer-research)

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