At BioIVT, we understand the importance of mutation analysis in cancer research. Our scientists routinely perform DNA and RNA isolation from both FFPE and Fresh Frozen tissues, as well as biofluids. Additionally, we utilize PCR and FISH for the determining the presence and/or location of particular mutations within tissue specimens. Standard mutation analysis is available for lung, skin, and colon cancers, with custom mutation screens available upon request.
It’s widely known that mutations such as KRAS occur in the early stages of cancer development. Thus, researchers are working diligently to develop specific therapeutic agents that target tumor cells via these predictive biomarkers (http://www.nature.com/oncsis/journal/v5/n8/full/oncsis201647a.html). For these researchers, it is critically important to utilize samples that have been processed via a strict and standardized process to assist in treatment effectivity.
For more information on how we can help you with your tissue and/or mutation analysis needs, please feel free to contact us.